Intrarenal Dopamine Production and Distribution in the Rat
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چکیده
منابع مشابه
Intrarenal dopamine production and distribution in the rat. Physiological control of sodium excretion.
Dopamine (DA), produced by the renal proximal tubule, has been demonstrated as an intrarenal paracrine hormone mediating diuresis and natriuresis. The precise mechanism by which DA exerts its cell-to-cell action is not fully understood. In the present study, renal interstitial fluid (RIF) DA (by in vivo microdialysis) and urinary DA excretion (UDAV) were compared in anesthetized rats on either ...
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OBJECTIVE: To investigate the organ distribution of dopamine transporter (DAT) in rats by immunohistochemical method. METHODS: Dopamine transporter (DAT) was identified immunohistochemically in the tissues using specific antipeptide antiserum raised in New Zealand white rabbits immunized with a conjugate of synthetic DAT peptide (29-45) with bovine serum albumin. Immunohistochemical analysis wa...
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The kidney has a local intrarenal dopaminergic system, and in the kidney, dopamine modulates renal hemodynamics, inhibits salt and fluid reabsorption, antagonizes the renin-angiotensin system, and inhibits oxidative stress. The current study examined the effects of alterations in the intrarenal dopaminergic system on kidney structure and function in models of type 1 diabetes. We studied catecho...
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15 صفحه اولDistribution of D2 dopamine receptor mRNA in rat brain.
The distribution of mRNA coding for the D2 dopamine receptor was studied in the rat brain by in situ hybridization. A cDNA probe corresponding to the putative third cytosolic loop and sixth and seventh transmembrane domains of the rat D2 receptor was used to generate an 35S-labeled riboprobe to hybridize to D2 receptor mRNA. D2 mRNA was found both in dopamine projection fields and in regions as...
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ژورنال
عنوان ژورنال: Hypertension
سال: 1997
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.29.1.228